HyperGraphs.jl is a Julia package that implements hypergraphs. These are a generalization of graphs that allow us to represent n-ary relationships and not just binary, pairwise relationships. High-order interactions are commonplace in biological systems and are of critical importance to their dynamics; hypergraphs thus offer a natural way to accurately describe and model these systems.;HyperGraphs.jl is freely available under the MIT license. Source code and documentation can be found at https://github.com/lpmdiaz/HyperGraphs.jl.;Supplementary data are available at Bioinformatics online.